Throughout the CONDOR HEROES TRILOGY, there were incidents of even the Greats having their pressure points sealed by inferior-level fighters (almost always through some kind of deception that left the Great off-guard). I forget specific incidents of Elite level DEMIGODS & SEMIDEVILS fighters (i.e. Janitor Monk, Hui Juk, Kiu Fung, Mo Yung Bok, Siu Yeun San, etc.) having their pressure points sealed, but I figure . . . if even the Greats can have their pressure points sealed, is there really no defense against this? On the one hand, it would be a good defense against these kinds of attacks. On the other hand, this could be potentially harmful to the practitioner because certain kinds of wounds and illnesses (i.e. internal injuries, blood loss, poisoning) are best treated via the sealing of acupoints. If one were invulnerable to acupoint sealing, then the healing aspects of the art would become unavailable as well.
But bottom line: is it even possible? Is there a martial art that renders the acupoints unsealable?